$850.00
Rapid Cell-Based SARS-CoV-2 Neutralizing Antibody Assay Kit
New HV-1 and JN-1 Variant Particles are Now Available! RCSNAK-01
Product Description
Product Description
Rapid Cell-Based SARS-CoV-2 Neutralizing Antibody Assay Kit
 New HV-1 and JN-1 Variant Particles are Now Available!
The entry of SARS-CoV-2 into host cells is mediated by the trimeric transmembrane spike (S) glycoprotein. The S glycoprotein is surface-exposed and mediates entry into the host cells by binding to the human angiotensin-converting enzyme 2 receptor which makes the S glycoprotein a major target of neutralizing antibodies. Neutralizing antibodies blocking the S protein and receptor binding could prevent the virus from infecting host cells. Through the detection of the luminescence levels of target cells, it is possible to screen or verify the activity of these neutralizing antibodies.
Our product is fundamentally superior to any of our competitors due to the implementation of our newly developed Ha-CoV-2 particle. Ha-CoV-2 is a newly developed hybrid SARS-CoV-2 virus-like particle (VLP) that encapsulates an alphavirus-derived RNA genome for rapid expression of reporter genes (luciferase or GFP) in target cells (Hetrick et al., 2022). Different from commonly used S protein pseudotyped lenti- or vesicular stomatitis virus (VSV)-pseudoviruses, Ha-CoV-2 is assembled with all 4 structural proteins (S, M, N, and E) of SARS-CoV-2, and contains a reporter genome derived from an alphavirus-based vector for rapid (4 hours) and robust expression of reporter genes. Ha-CoV-2 represents a major technology advancement in the development of SARS-CoV-2 pseudoviruses, and serves as platforms for rapid and robust quantification of neutralizing antibodies, viral mutants, and antiviral drugs (Dabbagh et al., 2021; He et al., 2021).
Virongy offers pre-assembled Ha-CoV-2 reporter pseudovirions and derived S protein variants. We also help customers to perform antiviral drug screening and quantification of neutralizing antibodies. For more information, please contact us by email: info@virongy.com
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Ha-CoV-2 Major advances
- A simple protocol that is easier than an ELISA based method
- Higher Accuracy than a traditional ELISA based neutralization assay
- Faster speed compared to other pseudoviruses– (Maximum reporter expression between 12-18 hours)
- More robust reporter signal – Ha-CoV-2 takes advantage of the rapid and robust gene expression capacity of an alphavirus vector for reporter expression.
- High fidelity in particle structure – Ha-CoV-2 contains all 4 SARS-CoV-2 structural proteins (S, M, E, and N), but no structural proteins from other viruses. In contrast, lenti- and VSV- pseudoviruses contain only the S protein from SARS-CoV-2, and multiple structural proteins from other viruses, such as HIV-1 Gag and Pol.
- Strong correlation (coefficient value r2 = 0.87) with wild-type SARS-CoV-2 in neutralizing antibody assays (Hetrick et al., 2020).
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Customize your kit by selecting from our list of SARS-CoV-2 spike mutants or variants:
| SARS-CoV-2 Spikes Available | Spike Mutations | Full Protein Sequences |
|---|---|---|
| D614G Single AA Mutant | Spike D614G | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVEGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Alpha (B.1.1.7) | Spike A570D, Spike D614G, Spike D1118H, Spike H69del, Spike N501Y, Spike P681H, Spike S982A, Spike T716I, Spike V70del, Spike Y145del | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLVRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGKIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV EGFNCYFPLQSYGFQPTYGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIDDTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTQTNSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPINFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILAR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTHNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| (B.1.1.207) | Spike D614G, Spike E484K, Spike P681H | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| (B.1.1.298) | Spike D614G, Spike H69del, Spike I692V, Spike M1229I, Spike V70del, Spike Y453F | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYYHKNNKSWMESEFRVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSA LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGKIADYN YKLPDDFTGCVIAWNSNNLD SKVGGNYNYLFRLFRKSNLK PFERDISTEIYQAGSTPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSPR RARSVASQSVIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQDVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVIVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| (B.1.2) | Spike D614G, Spike E484K, Spike G446V, Spike Y453F | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVVGNYNYLFRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| (B.1.258) | Spike D614G, Spike H69del, Spike N439K, Spike V70del | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYYHKNNKSWMESEFRVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSA LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGKIADYN YKLPDDFTGCVIAWNSKNLD SKVGGNYNYLYRLFRKSNLK PFERDISTEIYQAGSTPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSPR RARSVASQSIIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQDVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVMVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| Beta (B.1.351) | Spike A243del, Spike A701V, Spike D80A, Spike D215G, Spike D614G, Spike E484K, Spike K417N, Spike L242del, Spike L244del, Spike N501Y | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFA NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRGLPQGF SALEPLVDLPIGINITRFQT LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV KGFNCYFPLQSYGFQPTYGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTQTNSPRR ARSVASQSIIAYTMSLGVEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| Epsilon (B.1.429) | Spike A222V, Spike D614G, Spike L452R, Spike S13I, Spike W152C | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFA NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRGLPQGF SALEPLVDLPIGINITRFQT LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV KGFNCYFPLQSYGFQPTYGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTQTNSPRR ARSVASQSIIAYTMSLGVEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| (B.1.494) | Spike A262S, Spike D614G, Spike D796Y, Spike H49Y, Spike L452R, Spike N501Y, Spike P681R, Spike Q613H | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLYSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GSAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYRYRLFRKSN LKPFERDISTEIYQAGSTPC NGVEGFNCYFPLQSYGFQPT YGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYHGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS RRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKYFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Gamma (P.1) | Spike D138Y, Spike D614G, Spike E484K, Spike H655Y, Spike K417T, Spike L18F, Spike N501Y, Spike P26S, Spike R190S, Spike T20N, Spike T1027I, Spike V1176F | MFVFLVLLPLVSSQCVNFTN RTQLPSAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNYPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLSEFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGTIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT YGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEYVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAAIKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASFVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Kappa (B.1.617.1) | Spike E154K, Spike L452R, Spike E484Q, Spike D614G, Spike P681R, Spike Q1071H | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMKSEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYRYRLFRKSN LKPFERDISTEIYQAGSTPC NGVQGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS RRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAHEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Eta (B.1.525) | Spike A67V, Spike D614G, Spike E484K, Spike F888L, Spike H69del, Spike Q52R, Spike Q677H, Spike V70del, Spike Y144del | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTRDLFLPFFS NVTWFHVISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLVRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGKIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV KGFNCYFPLQSYGFQPTNGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTHTNSPRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTLGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| Epsilon (B.1.427/429) | Spike D614G, Spike E484K, Spike L452R, Spike S13I, Spike W152C | MFVFLVLLPLVSIQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSCMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYRYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Delta (B.1.617.2) | Spike T19R, Spike del157/158, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N | MFVFLVLLPLVSSQCVNLRT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSA LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGKIADYN YKLPDDFTGCVIAWNSNNLD SKVGGNYNYRYRLFRKSNLK PFERDISTEIYQAGSKPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSRR RARSVASQSIIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQNVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVMVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| Delta Plus (AY.2) | Spike T19R, Spike V70F, Spiked del157/158, Spike A222V, Spike K417N, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N | MFVFLVLLPLVSSQCVNLRT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHFSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSV LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGNIADYN YKLPDDFTGCVIAWNSNNLD SKVGGNYNYRYRLFRKSNLK PFERDISTEIYQAGSKPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSRR RARSVASQSIIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQNVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVMVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| Lambda (C.37) | Spike G75V, Spike T76I, Spike R246N, Spike del247/253, Spike L452Q, Spike F490S, Spike D614G, Spike T859N | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNVIKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHNSSSGWTAGAAAYYV GYLQPRTFLLKYNENGTITD AVDCALDPLSETKCTLKSFT VEKGIYQTSNFRVQPTESIV RFPNITNLCPFGEVFNATRF ASVYAWNRKRISNCVADYSV LYNSASFSTFKCYGVSPTKL NDLCFTNVYADSFVIRGDEV RQIAPGQTGKIADYNYKLPD DFTGCVIAWNSNNLDSKVGG NYNYQYRLFRKSNLKPFERD ISTEIYQAGSTPCNGVEGFN CYSPLQSYGFQPTNGVGYQP YRVVVLSFELLHAPATVCGP KKSTNLVKNKCVNFNFNGLT GTGVLTESNKKFLPFQQFGR DIADTTDAVRDPQTLEILDI TPCSFGGVSVITPGTNTSNQ VAVLYQGVNCTEVPVAIHAD QLTPTWRVYSTGSNVFQTRA GCLIGAEHVNNSYECDIPIG AGICASYQTQTNSPRRARSV ASQSIIAYTMSLGAENSVAY SNNSIAIPTNFTISVTTEIL PVSMTKTSVDCTMYICGDST ECSNLLLQYGSFCTQLNRAL TGIAVEQDKNTQEVFAQVKQ IYKTPPIKDFGGFNFSQILP DPSKPSKRSFIEDLLFNKVT LADAGFIKQYGDCLGDIAAR DLICAQKFNGLNVLPPLLTD EMIAQYTSALLAGTITSGWT FGAGAALQIPFAMQMAYRFN GIGVTQNVLYENQKLIANQF NSAIGKIQDSLSSTASALGK LQDVVNQNAQALNTLVKQLS SNFGAISSVLNDILSRLDKV EAEVQIDRLITGRLQSLQTY VTQQLIRAAEIRASANLAAT KMSECVLGQSKRVDFCGKGY HLMSFPQSAPHGVVFLHVTY VPAQEKNFTTAPAICHDGKA HFPREGVFVSNGTHWFVTQR NFYEPQIITTDNTFVSGNCD VVIGIVNNTVYDPLQPELDS FKEELDKYFKNHTSPDVDLG DISGINASVVNIQKEIDRLN EVAKNLNESLIDLQELGKYE QYIKWPWYIWLGFIAGLIAI VMVTIMLCCMTSCCSCLKGC CSCGSCCKFDEDDSEPVLKG VKLHYT |
| Mu (B.1.621) | Spike T95I, Spike Y144S, Spike Y145N, Spike R346K, Spike E484K, Spike N501Y, Spike D614G, Spike P681H, Spike D950N | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASIEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVSNHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATKFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT YGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQNVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Omicron (B.1.1.529) | Spike A67V, Spike H69del,Spike V70del, Spike T95I, Spike G142D, Spike V143del, Spike Y144del, Spike Y145del, Spike N211del, Spike L212I, Spike ins214EPE, Spike G339D, Spike S371L, Spike S373P, Spike S375F, Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike N969K, Spike L981F | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHVISGTNGTKRFDNP VLPFNDGVYFASIEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLD HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPIIVREPEDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFDEVFN ATRFASVYAWNRKRISNCVA DYSVLYNLAPFFTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KVSGNYNYLYRLFRKSNLKP FERDISTEIYQAGNKPCNGV AGFNCYFPLRSYSFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLKGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFKGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDIFSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| BA.2 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFDEVFN ATRFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGNKPCNGV AGFNCYFPLRSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| AY.4/BA.1 | Spike T19R, Spike A27S, Spike T95I, Spike G142D, Spike E156G, Spike F157del, Spike R158del, Spike ins214EPE, Spike N211del, Spike L212I, Spike G339D, Spike S371L, Spike S373P, Spike S375F Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike L981F, Spike N969K | MFVFLVLLPLVSSQCVNLRT RTQLPPSYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASIEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LDVYYHKNNKSWMESGVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPIIVREPEDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFDE VFNATRFASVYAWNRKRISN CVADYSVLYNLAPFFTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGNIAD YNYKLPDDFTGCVIAWNSNK LDSKVSGNYNYLYRLFRKSN LKPFERDISTEIYQAGNKPC NGVAGFNCYFPLRSYSFRPT YGVGHQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLKGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEYVNNSY ECDIPIGAGICASYQTQTKS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLKRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKYFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFKGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNHNAQALN TLVKQLSSKFGAISSVLNDI FSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| BA.4 and BA.5 (Share the Same Spike Mutations) | Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D,Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPINLGRDLPQGFSALEP LVDLPIGINITRFQTLLALH RSYLTPGDSSSGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFDEVFNAT RFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSKV GGNYNYRYRLFRKSNLKPFE RDISTEIYQAGNKPCNGVAG VNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNNSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAENSV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| BA.2.12.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452Q, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike S704L, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFDEVFN ATRFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KVGGNYNYQYRLFRKSNLKP FERDISTEIYQAGNKPCNGV AGFNCYFPLRSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN LVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| BA.2.75 | Spike T19I, Spike K147E, Spike W152R, Spike F157L, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASIEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHENNKSRMESELRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPVNLGRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSSWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFHE VFNATRFASVYAWNRKRISN CVADYSVLYNFAPFFAFKCY GVSPTKLNDLCFTNVYADSF VIRGNEVSQIAPGQTGNIAD YNYKLPDDFTGCVIAWNSNK LDSKVSGNYNYLYRLFRKSK LKPFERDISTEIYQAGNKPC NGVAGFNCYFPLQSYGFRPT YGVGHQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEYVNNSY ECDIPIGAGICASYQTQTKS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLKRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKYFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNHNAQALN TLVKQLSSKFGAISSVLNDI FSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| BA.4.6 | Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N658S, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPINLGRDLPQGFSALEP LVDLPIGINITRFQTLLALH RSYLTPGDSSSGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFDEVFNAT TFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSKV GGNYNYRYRLFRKSNLKPFE RDISTEIYQAGNKPCNGVAG VNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNSSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAENSV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| BQ.1.1 | Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P,Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPINLGRDLPQGFSALEP LVDLPIGINITRFQTLLALH RSYLTPGDSSSGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFDEVFNAT TFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSTV GGNYNYRYRLFRKSKLKPFE RDISTEIYQAGNKPCNGVAG VNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNNSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAENSV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| XBB.1 | Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GSNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.5 | Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.16 | Spike T19I, Spike L24S, Spike 25/27del, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, SpikeE180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S,Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.9.1 | Spike T19I, Spike L24S, Spike Del25/27, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPGDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| BA.2.86 | Spike ins16MPLF, Spike T19I, Spike R21T, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike S50L, Spike H69del, Spike V70del, Spike V127F, Spike G142D, Spike Y144del, Spike F157S, Spike R158G, Spike N211del, Spike L212I, Spike V213G, Spike L216F, Spike H245N, Spike A264D, Spike I332V, Spike G339H, Spike K356T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445H, Spike G446S, Spike N450D, Spike L452W, Spike N460K, Spike S477N, Spike T478K, Spike N481K, Spike V483del, Spike E484K, Spike F486P, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike A570V, Spike D614G, Spike P621S, Spike H655Y, Spike I670V, Spike N679K, Spike P681R, Spike N764K, Spike D796Y, Spike S939F, Spike Q954H, Spike N969K, Spike P1143L | MFVFLVLLPLVSSQCVMPLF NLITTTQSYTNSFTRGVYYP DKVFRSSVLHLTQDLFLPFF SNVTWFHAISGTNGTKRFDN PVLPFNDGVYFASTEKSNII RGWIFGTTLDSKTQSLLIVN NATNVFIKVCEFQFCNDPFL DVYHKNNKSWMESESGVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPIIGRDFPQGFSAL EPLVDLPIGINITRFQTLLA LNRSYLTPGDSSSGWTAGAA DYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNVTNLCPFHEVFN ATRFASVYAWNRTRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIK GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KHSGNYDYWYRLFRKSKLKP FERDISTEIYQAGNKPCKGK GPNCYFPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIVDTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVSVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGVCASYQTQTKSRRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLFSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQLE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| EG.5.1 | Spike A27S, Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| FL.1.5.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike L176F, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike F456L, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike A701V, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFFMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLLRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGVENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HV.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike Q52H, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike F157L, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L452R, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTHDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESELRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYRYRLLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| FL.10.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.16.11 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike E180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike P521T, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHATATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HK.3 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike Q52H, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike P809S, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTHDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDSSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HF.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike E180V, Spike Q183E, Spike V213E, Spike G252V, Spike K304N, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLN SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| JF.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike E180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HW.1.1 | Spike T19I, Spike P25S, Spike G142D, Spike Y144del, Spike E156G, Spike F157del, Spike R158del, Spike P209L, Spike L212S, Spike D215H, Spike A222V, Spike A243del, Spike L244del, Spike S256L, Spike R346S, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike G446S, Spike L452R, Spike N460H, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N703I, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQLSPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LDVYHKNNKSWMESGVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTLINSVRHLPQGFSVL EPLVDLPIGINITRFQTLLH RSYLTPGDSSLGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFGEVFNAT SFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSKV SGNYNYRYRLFRKSHLKPFE RDISTEIYQAGNKPCNGVAG PNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNNSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAEISV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| CH.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike K147E, Spike W152R, Spike F157L, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike G446S, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHENNKSRMESELRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPVNLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSSWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFHEVFN ATTFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS TVSGNYNYRYRLFRKSKLKP FERDISTEIYQAGNKPCNGV AGSNCYFPLQSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| DV.7.1.2 | Spike S12F, Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike K147E, Spike W152R, Spike F157L, Spike N185D, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike G446S, Spike L452R, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike L858I, Spike Q954H, Spike N969K | MFVFLVLLPLVFSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHENNKSRMESELRVYSSA NNCTFEYVSQPFLMDLEGKQ GDFKNLREFVFKNIDGYFKI YSKHTPVNLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSSWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFHEVFN ATTFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS TVSGNYNYRYRFLRKSKLKP FERDISTEIYQAGNKPCNGV AGSNCYFPLQSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGITVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| JH.2 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike H69del, Spike V70del, Spike G142D, Spike K147E, Spike F186Y, Spike K187del, Spike N188del, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike V445A, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484K, Spike F486A, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike I666V, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HENNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN YLREFVFKNIDGYFKIYSKH TPINLGRDLPQGFSALEPLV DLPIGINITRFQTLLALHRS YLTPGDSSSGWTAGAAAYYV GYLQPRTFLLKYNENGTITD AVDCALDPLSETKCTLKSFT VEKGIYQTSNFRVQPTESIV RFPNITNLCPFDEVFNATTF ASVYAWNRKRISNCVADYSV LYNFAPFFAFKCYGVSPTKL NDLCFTNVYADSFVIRGNEV SQIAPGQTGNIADYNYKLPD DFTGCVIAWNSNKLDSTAGG NYNYRYRLFRKSKLKPFERD ISTEIYQAGNKPCNGVKGAN CYFPLQSYGFRPTYGVGHQP YRVVVLSFELLHAPATVCGP KKSTNLVKNKCVNFNFNGLT GTGVLTESNKKFLPFQQFGR DIADTTDAVRDPQTLEILDI TPCSFGGVSVITPGTNTSNQ VAVLYQGVNCTEVPVAIHAD QLTPTWRVYSTGSNVFQTRA GCLIGAEYVNNSYECDIPVG AGICASYQTQTKSHRRARSV ASQSIIAYTMSLGAENSVAY SNNSIAIPTNFTISVTTEIL PVSMTKTSVDCTMYICGDST ECSNLLLQYGSFCTQLKRAL TGIAVEQDKNTQEVFAQVKQ IYKTPPIKYFGGFNFSQILP DPSKPSKRSFIEDLLFNKVT LADAGFIKQYGDCLGDIAAR DLICAQKFNGLTVLPPLLTD EMIAQYTSALLAGTITSGWT FGAGAALQIPFAMQMAYRFN GIGVTQNVLYENQKLIANQF NSAIGKIQDSLSSTASALGK LQDVVNHNAQALNTLVKQLS SKFGAISSVLNDILSRLDKV EAEVQIDRLITGRLQSLQTY VTQQLIRAAEIRASANLAAT KMSECVLGQSKRVDFCGKGY HLMSFPQSAPHGVVFLHVTY VPAQEKNFTTAPAICHDGKA HFPREGVFVSNGTHWFVTQR NFYEPQIITTDNTFVSGNCD VVIGIVNNTVYDPLQPELDS FKEELDKYFKNHTSPDVDLG DISGINASVVNIQKEIDRLN EVAKNLNESLIDLQELGKYE QYIKWPWYIWLGFIAGLIAI VMVTIMLCCMTSCCSCLKGC CSCGSCCKFDEDDSEPVLKG VKLHYT |
| JP.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V36I, Spike G142D, Spike K147E, Spike W152R, Spike F157L, Spike G181E, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike G446S, Spike L452R, Spike N460K, Spike S477N, Spike E484A, Spike F486S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K, Spike G1219V | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGIYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHENNKSRMESELRVYSSA NNCTFEYVSQPFLMDLEEKQ GNFKNLREFVFKNIDGYFKI YSKHTPVNLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSSWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFHEVFN ATTFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIK GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS TVSGNYNYRYRLFRKSKLKP FERDISTEIYQAGNTPCNGV AGSNCYFPLQSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLVFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| JN.1 | Spike ins16MPLF, Spike T19I, Spike R21T, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike S50L, Spike H69del, Spike V70del, Spike V127F, Spike G142D, Spike Y144del, Spike F157S, Spike R158G, Spike N211del, Spike L212I, Spike V213G, Spike L216F, Spike H245N, Spike A264D, Spike I332V, Spike G339H, Spike K356T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445H, Spike G446S, Spike N450D, Spike L452W, Spike L455S, Spike N460K, Spike S477N, Spike T478K, Spike N481K, Spike V483del, Spike E484K, Spike F486P, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike A570V, Spike D614G, Spike P621S, Spike H655Y, Spike N679K, Spike P681R, Spike N764K, Spike D796Y, Spike S939F, Spike Q954H, Spike N969K, Spike P1143L | MFVFLVLLPLVSSQCVMPLF NLITTTQSYTNSFTRGVYYP DKVFRSSVLHLTQDLFLPFF SNVTWFHAISGTNGTKRFDN PVLPFNDGVYFASTEKSNII RGWIFGTTLDSKTQSLLIVN NATNVFIKVCEFQFCNDPFL DVYHKNNKSWMESESGVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPIIGRDFPQGFSAL EPLVDLPIGINITRFQTLLA LNRSYLTPGDSSSGWTAGAA DYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNVTNLCPFHEVFN ATRFASVYAWNRTRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIK GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KHSGNYDYWYRSFRKSKLKP FERDISTEIYQAGNKPCKGK GPNCYFPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIVDTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVSVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSRRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLFSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQLE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| JD.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike A475V, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQVGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| GW.5.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike F79S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike A475V, Spike S477N, Spike T478I, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRSDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQVGNIPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| EG.10.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike A344T, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q493K, Spike S494P, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike A701V, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNT TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIKG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLKPYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGVENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.2.3 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike T95I, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike D253G, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike P521S, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASIEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPGGSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHASATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.41.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike L335S, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNSCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIKG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| JB.2.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike F140I, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike H245Y, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554D, Spike L582F, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPILDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL YRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIKG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTDSNKKFLPFQQ FGRDIADTTDAVRDPQTFEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHY |
| GK.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T573I, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike S704L, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTIDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENL VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
SARS-CoV-2 Neutralizing Antibody Assay Kit – HandbookVariant Information
Variant Information
| SARS-CoV-2 Spikes Available | Spike Mutations | Full Protein Sequences |
|---|---|---|
| D614G Single AA Mutant | Spike D614G | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVEGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Alpha (B.1.1.7) | Spike A570D, Spike D614G, Spike D1118H, Spike H69del, Spike N501Y, Spike P681H, Spike S982A, Spike T716I, Spike V70del, Spike Y145del | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLVRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGKIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV EGFNCYFPLQSYGFQPTYGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIDDTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTQTNSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPINFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILAR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTHNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| (B.1.1.207) | Spike D614G, Spike E484K, Spike P681H | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| (B.1.1.298) | Spike D614G, Spike H69del, Spike I692V, Spike M1229I, Spike V70del, Spike Y453F | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYYHKNNKSWMESEFRVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSA LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGKIADYN YKLPDDFTGCVIAWNSNNLD SKVGGNYNYLFRLFRKSNLK PFERDISTEIYQAGSTPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSPR RARSVASQSVIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQDVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVIVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| (B.1.2) | Spike D614G, Spike E484K, Spike G446V, Spike Y453F | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVVGNYNYLFRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| (B.1.258) | Spike D614G, Spike H69del, Spike N439K, Spike V70del | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYYHKNNKSWMESEFRVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSA LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGKIADYN YKLPDDFTGCVIAWNSKNLD SKVGGNYNYLYRLFRKSNLK PFERDISTEIYQAGSTPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSPR RARSVASQSIIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQDVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVMVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| Beta (B.1.351) | Spike A243del, Spike A701V, Spike D80A, Spike D215G, Spike D614G, Spike E484K, Spike K417N, Spike L242del, Spike L244del, Spike N501Y | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFA NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRGLPQGF SALEPLVDLPIGINITRFQT LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV KGFNCYFPLQSYGFQPTYGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTQTNSPRR ARSVASQSIIAYTMSLGVEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| Epsilon (B.1.429) | Spike A222V, Spike D614G, Spike L452R, Spike S13I, Spike W152C | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFA NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRGLPQGF SALEPLVDLPIGINITRFQT LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV KGFNCYFPLQSYGFQPTYGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTQTNSPRR ARSVASQSIIAYTMSLGVEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| (B.1.494) | Spike A262S, Spike D614G, Spike D796Y, Spike H49Y, Spike L452R, Spike N501Y, Spike P681R, Spike Q613H | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLYSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GSAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYRYRLFRKSN LKPFERDISTEIYQAGSTPC NGVEGFNCYFPLQSYGFQPT YGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYHGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS RRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKYFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Gamma (P.1) | Spike D138Y, Spike D614G, Spike E484K, Spike H655Y, Spike K417T, Spike L18F, Spike N501Y, Spike P26S, Spike R190S, Spike T20N, Spike T1027I, Spike V1176F | MFVFLVLLPLVSSQCVNFTN RTQLPSAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNYPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLSEFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGTIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT YGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEYVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAAIKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASFVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Kappa (B.1.617.1) | Spike E154K, Spike L452R, Spike E484Q, Spike D614G, Spike P681R, Spike Q1071H | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMKSEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYRYRLFRKSN LKPFERDISTEIYQAGSTPC NGVQGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS RRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAHEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Eta (B.1.525) | Spike A67V, Spike D614G, Spike E484K, Spike F888L, Spike H69del, Spike Q52R, Spike Q677H, Spike V70del, Spike Y144del | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTRDLFLPFFS NVTWFHVISGTNGTKRFDNP VLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLG VYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLVRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFGEVFN ATRFASVYAWNRKRISNCVA DYSVLYNSASFSTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGKIADYNY KLPDDFTGCVIAWNSNNLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGSTPCNGV KGFNCYFPLQSYGFQPTNGV GYQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEHVNNSYECD IPIGAGICASYQTHTNSPRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL NRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKDFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTLGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNQNAQALNTLV KQLSSNFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| Epsilon (B.1.427/429) | Spike D614G, Spike E484K, Spike L452R, Spike S13I, Spike W152C | MFVFLVLLPLVSIQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSCMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATRFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYRYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT NGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS PRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Delta (B.1.617.2) | Spike T19R, Spike del157/158, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N | MFVFLVLLPLVSSQCVNLRT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSA LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGKIADYN YKLPDDFTGCVIAWNSNNLD SKVGGNYNYRYRLFRKSNLK PFERDISTEIYQAGSKPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSRR RARSVASQSIIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQNVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVMVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| Delta Plus (AY.2) | Spike T19R, Spike V70F, Spiked del157/158, Spike A222V, Spike K417N, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N | MFVFLVLLPLVSSQCVNLRT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHFSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPINLVRDLPQGFSV LEPLVDLPIGINITRFQTLL ALHRSYLTPGDSSSGWTAGA AAYYVGYLQPRTFLLKYNEN GTITDAVDCALDPLSETKCT LKSFTVEKGIYQTSNFRVQP TESIVRFPNITNLCPFGEVF NATRFASVYAWNRKRISNCV ADYSVLYNSASFSTFKCYGV SPTKLNDLCFTNVYADSFVI RGDEVRQIAPGQTGNIADYN YKLPDDFTGCVIAWNSNNLD SKVGGNYNYRYRLFRKSNLK PFERDISTEIYQAGSKPCNG VEGFNCYFPLQSYGFQPTNG VGYQPYRVVVLSFELLHAPA TVCGPKKSTNLVKNKCVNFN FNGLTGTGVLTESNKKFLPF QQFGRDIADTTDAVRDPQTL EILDITPCSFGGVSVITPGT NTSNQVAVLYQGVNCTEVPV AIHADQLTPTWRVYSTGSNV FQTRAGCLIGAEHVNNSYEC DIPIGAGICASYQTQTNSRR RARSVASQSIIAYTMSLGAE NSVAYSNNSIAIPTNFTISV TTEILPVSMTKTSVDCTMYI CGDSTECSNLLLQYGSFCTQ LNRALTGIAVEQDKNTQEVF AQVKQIYKTPPIKDFGGFNF SQILPDPSKPSKRSFIEDLL FNKVTLADAGFIKQYGDCLG DIAARDLICAQKFNGLTVLP PLLTDEMIAQYTSALLAGTI TSGWTFGAGAALQIPFAMQM AYRFNGIGVTQNVLYENQKL IANQFNSAIGKIQDSLSSTA SALGKLQNVVNQNAQALNTL VKQLSSNFGAISSVLNDILS RLDKVEAEVQIDRLITGRLQ SLQTYVTQQLIRAAEIRASA NLAATKMSECVLGQSKRVDF CGKGYHLMSFPQSAPHGVVF LHVTYVPAQEKNFTTAPAIC HDGKAHFPREGVFVSNGTHW FVTQRNFYEPQIITTDNTFV SGNCDVVIGIVNNTVYDPLQ PELDSFKEELDKYFKNHTSP DVDLGDISGINASVVNIQKE IDRLNEVAKNLNESLIDLQE LGKYEQYIKWPWYIWLGFIA GLIAIVMVTIMLCCMTSCCS CLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT |
| Lambda (C.37) | Spike G75V, Spike T76I, Spike R246N, Spike del247/253, Spike L452Q, Spike F490S, Spike D614G, Spike T859N | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNVIKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHNSSSGWTAGAAAYYV GYLQPRTFLLKYNENGTITD AVDCALDPLSETKCTLKSFT VEKGIYQTSNFRVQPTESIV RFPNITNLCPFGEVFNATRF ASVYAWNRKRISNCVADYSV LYNSASFSTFKCYGVSPTKL NDLCFTNVYADSFVIRGDEV RQIAPGQTGKIADYNYKLPD DFTGCVIAWNSNNLDSKVGG NYNYQYRLFRKSNLKPFERD ISTEIYQAGSTPCNGVEGFN CYSPLQSYGFQPTNGVGYQP YRVVVLSFELLHAPATVCGP KKSTNLVKNKCVNFNFNGLT GTGVLTESNKKFLPFQQFGR DIADTTDAVRDPQTLEILDI TPCSFGGVSVITPGTNTSNQ VAVLYQGVNCTEVPVAIHAD QLTPTWRVYSTGSNVFQTRA GCLIGAEHVNNSYECDIPIG AGICASYQTQTNSPRRARSV ASQSIIAYTMSLGAENSVAY SNNSIAIPTNFTISVTTEIL PVSMTKTSVDCTMYICGDST ECSNLLLQYGSFCTQLNRAL TGIAVEQDKNTQEVFAQVKQ IYKTPPIKDFGGFNFSQILP DPSKPSKRSFIEDLLFNKVT LADAGFIKQYGDCLGDIAAR DLICAQKFNGLNVLPPLLTD EMIAQYTSALLAGTITSGWT FGAGAALQIPFAMQMAYRFN GIGVTQNVLYENQKLIANQF NSAIGKIQDSLSSTASALGK LQDVVNQNAQALNTLVKQLS SNFGAISSVLNDILSRLDKV EAEVQIDRLITGRLQSLQTY VTQQLIRAAEIRASANLAAT KMSECVLGQSKRVDFCGKGY HLMSFPQSAPHGVVFLHVTY VPAQEKNFTTAPAICHDGKA HFPREGVFVSNGTHWFVTQR NFYEPQIITTDNTFVSGNCD VVIGIVNNTVYDPLQPELDS FKEELDKYFKNHTSPDVDLG DISGINASVVNIQKEIDRLN EVAKNLNESLIDLQELGKYE QYIKWPWYIWLGFIAGLIAI VMVTIMLCCMTSCCSCLKGC CSCGSCCKFDEDDSEPVLKG VKLHYT |
| Mu (B.1.621) | Spike T95I, Spike Y144S, Spike Y145N, Spike R346K, Spike E484K, Spike N501Y, Spike D614G, Spike P681H, Spike D950N | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASIEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVSNHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPINLVRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFGE VFNATKFASVYAWNRKRISN CVADYSVLYNSASFSTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGKIAD YNYKLPDDFTGCVIAWNSNN LDSKVGGNYNYLYRLFRKSN LKPFERDISTEIYQAGSTPC NGVKGFNCYFPLQSYGFQPT YGVGYQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEHVNNSY ECDIPIGAGICASYQTQTNS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLNRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKDFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQNVVNQNAQALN TLVKQLSSNFGAISSVLNDI LSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| Omicron (B.1.1.529) | Spike A67V, Spike H69del,Spike V70del, Spike T95I, Spike G142D, Spike V143del, Spike Y144del, Spike Y145del, Spike N211del, Spike L212I, Spike ins214EPE, Spike G339D, Spike S371L, Spike S373P, Spike S375F, Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike N969K, Spike L981F | MFVFLVLLPLVSSQCVNLTT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHVISGTNGTKRFDNP VLPFNDGVYFASIEKSNIIR GWIFGTTLDSKTQSLLIVNN ATNVVIKVCEFQFCNDPFLD HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPIIVREPEDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFDEVFN ATRFASVYAWNRKRISNCVA DYSVLYNLAPFFTFKCYGVS PTKLNDLCFTNVYADSFVIR GDEVRQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KVSGNYNYLYRLFRKSNLKP FERDISTEIYQAGNKPCNGV AGFNCYFPLRSYSFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLKGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFKGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDIFSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| BA.2 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFDEVFN ATRFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KVGGNYNYLYRLFRKSNLKP FERDISTEIYQAGNKPCNGV AGFNCYFPLRSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| AY.4/BA.1 | Spike T19R, Spike A27S, Spike T95I, Spike G142D, Spike E156G, Spike F157del, Spike R158del, Spike ins214EPE, Spike N211del, Spike L212I, Spike G339D, Spike S371L, Spike S373P, Spike S375F Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike L981F, Spike N969K | MFVFLVLLPLVSSQCVNLRT RTQLPPSYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASIEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LDVYYHKNNKSWMESGVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPIIVREPEDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSGWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFDE VFNATRFASVYAWNRKRISN CVADYSVLYNLAPFFTFKCY GVSPTKLNDLCFTNVYADSF VIRGDEVRQIAPGQTGNIAD YNYKLPDDFTGCVIAWNSNK LDSKVSGNYNYLYRLFRKSN LKPFERDISTEIYQAGNKPC NGVAGFNCYFPLRSYSFRPT YGVGHQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLKGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEYVNNSY ECDIPIGAGICASYQTQTKS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLKRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKYFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFKGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNHNAQALN TLVKQLSSKFGAISSVLNDI FSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| BA.4 and BA.5 (Share the Same Spike Mutations) | Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D,Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPINLGRDLPQGFSALEP LVDLPIGINITRFQTLLALH RSYLTPGDSSSGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFDEVFNAT RFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSKV GGNYNYRYRLFRKSNLKPFE RDISTEIYQAGNKPCNGVAG VNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNNSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAENSV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| BA.2.12.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452Q, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike S704L, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHKNNKSWMESEFRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPINLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSGWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFDEVFN ATRFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KVGGNYNYQYRLFRKSNLKP FERDISTEIYQAGNKPCNGV AGFNCYFPLRSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN LVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| BA.2.75 | Spike T19I, Spike K147E, Spike W152R, Spike F157L, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQLPPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASIEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LGVYYHENNKSRMESELRVY SSANNCTFEYVSQPFLMDLE GKQGNFKNLREFVFKNIDGY FKIYSKHTPVNLGRDLPQGF SALEPLVDLPIGINITRFQT LLALHRSYLTPGDSSSSWTA GAAAYYVGYLQPRTFLLKYN ENGTITDAVDCALDPLSETK CTLKSFTVEKGIYQTSNFRV QPTESIVRFPNITNLCPFHE VFNATRFASVYAWNRKRISN CVADYSVLYNFAPFFAFKCY GVSPTKLNDLCFTNVYADSF VIRGNEVSQIAPGQTGNIAD YNYKLPDDFTGCVIAWNSNK LDSKVSGNYNYLYRLFRKSK LKPFERDISTEIYQAGNKPC NGVAGFNCYFPLQSYGFRPT YGVGHQPYRVVVLSFELLHA PATVCGPKKSTNLVKNKCVN FNFNGLTGTGVLTESNKKFL PFQQFGRDIADTTDAVRDPQ TLEILDITPCSFGGVSVITP GTNTSNQVAVLYQGVNCTEV PVAIHADQLTPTWRVYSTGS NVFQTRAGCLIGAEYVNNSY ECDIPIGAGICASYQTQTKS HRRARSVASQSIIAYTMSLG AENSVAYSNNSIAIPTNFTI SVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFC TQLKRALTGIAVEQDKNTQE VFAQVKQIYKTPPIKYFGGF NFSQILPDPSKPSKRSFIED LLFNKVTLADAGFIKQYGDC LGDIAARDLICAQKFNGLTV LPPLLTDEMIAQYTSALLAG TITSGWTFGAGAALQIPFAM QMAYRFNGIGVTQNVLYENQ KLIANQFNSAIGKIQDSLSS TASALGKLQDVVNHNAQALN TLVKQLSSKFGAISSVLNDI FSRLDKVEAEVQIDRLITGR LQSLQTYVTQQLIRAAEIRA SANLAATKMSECVLGQSKRV DFCGKGYHLMSFPQSAPHGV VFLHVTYVPAQEKNFTTAPA ICHDGKAHFPREGVFVSNGT HWFVTQRNFYEPQIITTDNT FVSGNCDVVIGIVNNTVYDP LQPELDSFKEELDKYFKNHT SPDVDLGDISGINASVVNIQ KEIDRLNEVAKNLNESLIDL QELGKYEQYIKWPWYIWLGF IAGLIAIVMVTIMLCCMTSC CSCLKGCCSCGSCCKFDEDD SEPVLKGVKLHYT |
| BA.4.6 | Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N658S, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPINLGRDLPQGFSALEP LVDLPIGINITRFQTLLALH RSYLTPGDSSSGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFDEVFNAT TFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSKV GGNYNYRYRLFRKSNLKPFE RDISTEIYQAGNKPCNGVAG VNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNSSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAENSV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| BQ.1.1 | Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P,Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HKNNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN FKNLREFVFKNIDGYFKIYS KHTPINLGRDLPQGFSALEP LVDLPIGINITRFQTLLALH RSYLTPGDSSSGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFDEVFNAT TFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSTV GGNYNYRYRLFRKSKLKPFE RDISTEIYQAGNKPCNGVAG VNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNNSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAENSV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| XBB.1 | Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GSNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.5 | Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.16 | Spike T19I, Spike L24S, Spike 25/27del, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, SpikeE180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S,Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.9.1 | Spike T19I, Spike L24S, Spike Del25/27, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPGDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| BA.2.86 | Spike ins16MPLF, Spike T19I, Spike R21T, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike S50L, Spike H69del, Spike V70del, Spike V127F, Spike G142D, Spike Y144del, Spike F157S, Spike R158G, Spike N211del, Spike L212I, Spike V213G, Spike L216F, Spike H245N, Spike A264D, Spike I332V, Spike G339H, Spike K356T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445H, Spike G446S, Spike N450D, Spike L452W, Spike N460K, Spike S477N, Spike T478K, Spike N481K, Spike V483del, Spike E484K, Spike F486P, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike A570V, Spike D614G, Spike P621S, Spike H655Y, Spike I670V, Spike N679K, Spike P681R, Spike N764K, Spike D796Y, Spike S939F, Spike Q954H, Spike N969K, Spike P1143L | MFVFLVLLPLVSSQCVMPLF NLITTTQSYTNSFTRGVYYP DKVFRSSVLHLTQDLFLPFF SNVTWFHAISGTNGTKRFDN PVLPFNDGVYFASTEKSNII RGWIFGTTLDSKTQSLLIVN NATNVFIKVCEFQFCNDPFL DVYHKNNKSWMESESGVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPIIGRDFPQGFSAL EPLVDLPIGINITRFQTLLA LNRSYLTPGDSSSGWTAGAA DYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNVTNLCPFHEVFN ATRFASVYAWNRTRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIK GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KHSGNYDYWYRLFRKSKLKP FERDISTEIYQAGNKPCKGK GPNCYFPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIVDTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVSVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGVCASYQTQTKSRRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLFSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQLE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| EG.5.1 | Spike A27S, Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| FL.1.5.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike L176F, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike F456L, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike A701V, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFFMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLLRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGVENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HV.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike Q52H, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike F157L, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L452R, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTHDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESELRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYRYRLLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| FL.10.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.16.11 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike E180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike P521T, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHATATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HK.3 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike Q52H, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike P809S, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTHDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDSSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HF.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike E180V, Spike Q183E, Spike V213E, Spike G252V, Spike K304N, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLN SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| JF.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike E180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLVGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| HW.1.1 | Spike T19I, Spike P25S, Spike G142D, Spike Y144del, Spike E156G, Spike F157del, Spike R158del, Spike P209L, Spike L212S, Spike D215H, Spike A222V, Spike A243del, Spike L244del, Spike S256L, Spike R346S, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike G446S, Spike L452R, Spike N460H, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N703I, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQLSPAYTNSFTRGVYYPD KVFRSSVLHSTQDLFLPFFS NVTWFHAIHVSGTNGTKRFD NPVLPFNDGVYFASTEKSNI IRGWIFGTTLDSKTQSLLIV NNATNVVIKVCEFQFCNDPF LDVYHKNNKSWMESGVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTLINSVRHLPQGFSVL EPLVDLPIGINITRFQTLLH RSYLTPGDSSLGWTAGAAAY YVGYLQPRTFLLKYNENGTI TDAVDCALDPLSETKCTLKS FTVEKGIYQTSNFRVQPTES IVRFPNITNLCPFGEVFNAT SFASVYAWNRKRISNCVADY SVLYNFAPFFAFKCYGVSPT KLNDLCFTNVYADSFVIRGN EVSQIAPGQTGNIADYNYKL PDDFTGCVIAWNSNKLDSKV SGNYNYRYRLFRKSHLKPFE RDISTEIYQAGNKPCNGVAG PNCYFPLQSYGFRPTYGVGH QPYRVVVLSFELLHAPATVC GPKKSTNLVKNKCVNFNFNG LTGTGVLTESNKKFLPFQQF GRDIADTTDAVRDPQTLEIL DITPCSFGGVSVITPGTNTS NQVAVLYQGVNCTEVPVAIH ADQLTPTWRVYSTGSNVFQT RAGCLIGAEYVNNSYECDIP IGAGICASYQTQTKSHRRAR SVASQSIIAYTMSLGAEISV AYSNNSIAIPTNFTISVTTE ILPVSMTKTSVDCTMYICGD STECSNLLLQYGSFCTQLKR ALTGIAVEQDKNTQEVFAQV KQIYKTPPIKYFGGFNFSQI LPDPSKPSKRSFIEDLLFNK VTLADAGFIKQYGDCLGDIA ARDLICAQKFNGLTVLPPLL TDEMIAQYTSALLAGTITSG WTFGAGAALQIPFAMQMAYR FNGIGVTQNVLYENQKLIAN QFNSAIGKIQDSLSSTASAL GKLQDVVNHNAQALNTLVKQ LSSKFGAISSVLNDILSRLD KVEAEVQIDRLITGRLQSLQ TYVTQQLIRAAEIRASANLA ATKMSECVLGQSKRVDFCGK GYHLMSFPQSAPHGVVFLHV TYVPAQEKNFTTAPAICHDG KAHFPREGVFVSNGTHWFVT QRNFYEPQIITTDNTFVSGN CDVVIGIVNNTVYDPLQPEL DSFKEELDKYFKNHTSPDVD LGDISGINASVVNIQKEIDR LNEVAKNLNESLIDLQELGK YEQYIKWPWYIWLGFIAGLI AIVMVTIMLCCMTSCCSCLK GCCSCGSCCKFDEDDSEPVL KGVKLHYT |
| CH.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike K147E, Spike W152R, Spike F157L, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike G446S, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHENNKSRMESELRVYSSA NNCTFEYVSQPFLMDLEGKQ GNFKNLREFVFKNIDGYFKI YSKHTPVNLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSSWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFHEVFN ATTFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS TVSGNYNYRYRLFRKSKLKP FERDISTEIYQAGNKPCNGV AGSNCYFPLQSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| DV.7.1.2 | Spike S12F, Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike K147E, Spike W152R, Spike F157L, Spike N185D, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike G446S, Spike L452R, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike L858I, Spike Q954H, Spike N969K | MFVFLVLLPLVFSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHENNKSRMESELRVYSSA NNCTFEYVSQPFLMDLEGKQ GDFKNLREFVFKNIDGYFKI YSKHTPVNLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSSWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFHEVFN ATTFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIR GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS TVSGNYNYRYRFLRKSKLKP FERDISTEIYQAGNKPCNGV AGSNCYFPLQSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGITVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLGFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| JH.2 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike H69del, Spike V70del, Spike G142D, Spike K147E, Spike F186Y, Spike K187del, Spike N188del, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike V445A, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484K, Spike F486A, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike I666V, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAISGTNGTKRFDNPVLP FNDGVYFASTEKSNIIRGWI FGTTLDSKTQSLLIVNNATN VVIKVCEFQFCNDPFLDVYY HENNKSWMESEFRVYSSANN CTFEYVSQPFLMDLEGKQGN YLREFVFKNIDGYFKIYSKH TPINLGRDLPQGFSALEPLV DLPIGINITRFQTLLALHRS YLTPGDSSSGWTAGAAAYYV GYLQPRTFLLKYNENGTITD AVDCALDPLSETKCTLKSFT VEKGIYQTSNFRVQPTESIV RFPNITNLCPFDEVFNATTF ASVYAWNRKRISNCVADYSV LYNFAPFFAFKCYGVSPTKL NDLCFTNVYADSFVIRGNEV SQIAPGQTGNIADYNYKLPD DFTGCVIAWNSNKLDSTAGG NYNYRYRLFRKSKLKPFERD ISTEIYQAGNKPCNGVKGAN CYFPLQSYGFRPTYGVGHQP YRVVVLSFELLHAPATVCGP KKSTNLVKNKCVNFNFNGLT GTGVLTESNKKFLPFQQFGR DIADTTDAVRDPQTLEILDI TPCSFGGVSVITPGTNTSNQ VAVLYQGVNCTEVPVAIHAD QLTPTWRVYSTGSNVFQTRA GCLIGAEYVNNSYECDIPVG AGICASYQTQTKSHRRARSV ASQSIIAYTMSLGAENSVAY SNNSIAIPTNFTISVTTEIL PVSMTKTSVDCTMYICGDST ECSNLLLQYGSFCTQLKRAL TGIAVEQDKNTQEVFAQVKQ IYKTPPIKYFGGFNFSQILP DPSKPSKRSFIEDLLFNKVT LADAGFIKQYGDCLGDIAAR DLICAQKFNGLTVLPPLLTD EMIAQYTSALLAGTITSGWT FGAGAALQIPFAMQMAYRFN GIGVTQNVLYENQKLIANQF NSAIGKIQDSLSSTASALGK LQDVVNHNAQALNTLVKQLS SKFGAISSVLNDILSRLDKV EAEVQIDRLITGRLQSLQTY VTQQLIRAAEIRASANLAAT KMSECVLGQSKRVDFCGKGY HLMSFPQSAPHGVVFLHVTY VPAQEKNFTTAPAICHDGKA HFPREGVFVSNGTHWFVTQR NFYEPQIITTDNTFVSGNCD VVIGIVNNTVYDPLQPELDS FKEELDKYFKNHTSPDVDLG DISGINASVVNIQKEIDRLN EVAKNLNESLIDLQELGKYE QYIKWPWYIWLGFIAGLIAI VMVTIMLCCMTSCCSCLKGC CSCGSCCKFDEDDSEPVLKG VKLHYT |
| JP.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V36I, Spike G142D, Spike K147E, Spike W152R, Spike F157L, Spike G181E, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike G446S, Spike L452R, Spike N460K, Spike S477N, Spike E484A, Spike F486S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K, Spike G1219V | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGIYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPV LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YYHENNKSRMESELRVYSSA NNCTFEYVSQPFLMDLEEKQ GNFKNLREFVFKNIDGYFKI YSKHTPVNLGRDLPQGFSAL EPLVDLPIGINITRFQTLLA LHRSYLTPGDSSSSWTAGAA AYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNITNLCPFHEVFN ATTFASVYAWNRKRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIK GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS TVSGNYNYRYRLFRKSKLKP FERDISTEIYQAGNTPCNGV AGSNCYFPLQSYGFRPTYGV GHQPYRVVVLSFELLHAPAT VCGPKKSTNLVKNKCVNFNF NGLTGTGVLTESNKKFLPFQ QFGRDIADTTDAVRDPQTLE ILDITPCSFGGVSVITPGTN TSNQVAVLYQGVNCTEVPVA IHADQLTPTWRVYSTGSNVF QTRAGCLIGAEYVNNSYECD IPIGAGICASYQTQTKSHRR ARSVASQSIIAYTMSLGAEN SVAYSNNSIAIPTNFTISVT TEILPVSMTKTSVDCTMYIC GDSTECSNLLLQYGSFCTQL KRALTGIAVEQDKNTQEVFA QVKQIYKTPPIKYFGGFNFS QILPDPSKPSKRSFIEDLLF NKVTLADAGFIKQYGDCLGD IAARDLICAQKFNGLTVLPP LLTDEMIAQYTSALLAGTIT SGWTFGAGAALQIPFAMQMA YRFNGIGVTQNVLYENQKLI ANQFNSAIGKIQDSLSSTAS ALGKLQDVVNHNAQALNTLV KQLSSKFGAISSVLNDILSR LDKVEAEVQIDRLITGRLQS LQTYVTQQLIRAAEIRASAN LAATKMSECVLGQSKRVDFC GKGYHLMSFPQSAPHGVVFL HVTYVPAQEKNFTTAPAICH DGKAHFPREGVFVSNGTHWF VTQRNFYEPQIITTDNTFVS GNCDVVIGIVNNTVYDPLQP ELDSFKEELDKYFKNHTSPD VDLGDISGINASVVNIQKEI DRLNEVAKNLNESLIDLQEL GKYEQYIKWPWYIWLVFIAG LIAIVMVTIMLCCMTSCCSC LKGCCSCGSCCKFDEDDSEP VLKGVKLHYT |
| JN.1 | Spike ins16MPLF, Spike T19I, Spike R21T, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike S50L, Spike H69del, Spike V70del, Spike V127F, Spike G142D, Spike Y144del, Spike F157S, Spike R158G, Spike N211del, Spike L212I, Spike V213G, Spike L216F, Spike H245N, Spike A264D, Spike I332V, Spike G339H, Spike K356T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445H, Spike G446S, Spike N450D, Spike L452W, Spike L455S, Spike N460K, Spike S477N, Spike T478K, Spike N481K, Spike V483del, Spike E484K, Spike F486P, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike A570V, Spike D614G, Spike P621S, Spike H655Y, Spike N679K, Spike P681R, Spike N764K, Spike D796Y, Spike S939F, Spike Q954H, Spike N969K, Spike P1143L | MFVFLVLLPLVSSQCVMPLF NLITTTQSYTNSFTRGVYYP DKVFRSSVLHLTQDLFLPFF SNVTWFHAISGTNGTKRFDN PVLPFNDGVYFASTEKSNII RGWIFGTTLDSKTQSLLIVN NATNVFIKVCEFQFCNDPFL DVYHKNNKSWMESESGVYSS ANNCTFEYVSQPFLMDLEGK QGNFKNLREFVFKNIDGYFK IYSKHTPIIGRDFPQGFSAL EPLVDLPIGINITRFQTLLA LNRSYLTPGDSSSGWTAGAA DYYVGYLQPRTFLLKYNENG TITDAVDCALDPLSETKCTL KSFTVEKGIYQTSNFRVQPT ESIVRFPNVTNLCPFHEVFN ATRFASVYAWNRTRISNCVA DYSVLYNFAPFFAFKCYGVS PTKLNDLCFTNVYADSFVIK GNEVSQIAPGQTGNIADYNY KLPDDFTGCVIAWNSNKLDS KHSGNYDYWYRSFRKSKLKP FERDISTEIYQAGNKPCKGK GPNCYFPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIVDTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVSVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSRRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLFSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQLE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| JD.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike A475V, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQVGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| GW.5.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike F79S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike A475V, Spike S477N, Spike T478I, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRSDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQVGNIPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTKSNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| EG.10.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike A344T, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q493K, Spike S494P, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike A701V, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNT TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIKG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLKPYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGVENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.2.3 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike T95I, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike D253G, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike P521S, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASIEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPGGSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHASATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| XBB.1.41.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike L335S, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNSCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIKG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTTDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
| JB.2.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike F140I, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike H245Y, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike R403K, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike E554D, Spike L582F, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPILDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL YRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIKG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRLFRKSKLKPF ERDISTEIYQAGNRPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTDSNKKFLPFQQ FGRDIADTTDAVRDPQTFEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENS VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHY |
| GK.1.1 | Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike V83A, Spike G142D, Spike Y144del, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike L455F, Spike F456L, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T573I, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike S704L, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K | MFVFLVLLPLVSSQCVNLIT RTQSYTNSFTRGVYYPDKVF RSSVLHSTQDLFLPFFSNVT WFHAIHVSGTNGTKRFDNPA LPFNDGVYFASTEKSNIIRG WIFGTTLDSKTQSLLIVNNA TNVVIKVCEFQFCNDPFLDV YQKNNKSWMESEFRVYSSAN NCTFEYVSQPFLMDLEGKEG NFKNLREFVFKNIDGYFKIY SKHTPINLERDLPQGFSALE PLVDLPIGINITRFQTLLAL HRSYLTPVDSSSGWTAGAAA YYVGYLQPRTFLLKYNENGT ITDAVDCALDPLSETKCTLK SFTVEKGIYQTSNFRVQPTE SIVRFPNITNLCPFHEVFNA TTFASVYAWNRKRISNCVAD YSVIYNFAPFFAFKCYGVSP TKLNDLCFTNVYADSFVIRG NEVSQIAPGQTGNIADYNYK LPDDFTGCVIAWNSNKLDSK PSGNYNYLYRFLRKSKLKPF ERDISTEIYQAGNKPCNGVA GPNCYSPLQSYGFRPTYGVG HQPYRVVVLSFELLHAPATV CGPKKSTNLVKNKCVNFNFN GLTGTGVLTESNKKFLPFQQ FGRDIADTIDAVRDPQTLEI LDITPCSFGGVSVITPGTNT SNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQ TRAGCLIGAEYVNNSYECDI PIGAGICASYQTQTKSHRRA RSVASQSIIAYTMSLGAENL VAYSNNSIAIPTNFTISVTT EILPVSMTKTSVDCTMYICG DSTECSNLLLQYGSFCTQLK RALTGIAVEQDKNTQEVFAQ VKQIYKTPPIKYFGGFNFSQ ILPDPSKPSKRSFIEDLLFN KVTLADAGFIKQYGDCLGDI AARDLICAQKFNGLTVLPPL LTDEMIAQYTSALLAGTITS GWTFGAGAALQIPFAMQMAY RFNGIGVTQNVLYENQKLIA NQFNSAIGKIQDSLSSTASA LGKLQDVVNHNAQALNTLVK QLSSKFGAISSVLNDILSRL DKVEAEVQIDRLITGRLQSL QTYVTQQLIRAAEIRASANL AATKMSECVLGQSKRVDFCG KGYHLMSFPQSAPHGVVFLH VTYVPAQEKNFTTAPAICHD GKAHFPREGVFVSNGTHWFV TQRNFYEPQIITTDNTFVSG NCDVVIGIVNNTVYDPLQPE LDSFKEELDKYFKNHTSPDV DLGDISGINASVVNIQKEID RLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGL IAIVMVTIMLCCMTSCCSCL KGCCSCGSCCKFDEDDSEPV LKGVKLHYT |
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