SARS-CoV-2 protein expression vector

SARS-CoV-2 Protein Expression Vectors

$350.00 – $800.00

The SARS-CoV-2 protein expression vectors are full-length, and codon optimized for mammalian cell expression.

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Protein Envelope, Membrane, Nucleocapsid, ORF7, ORF8, RNA-Dependent RNA Polymerase (RDRP), Spike
Variant Wild Type, XBB.1.9.1, XBB.1.16, D614G Single Mutation, XBB.1.5, XBB.1, BQ.1.1, BQ.1, BA.4.6, BA.2.75, BA.2.12.1, BA.4 and BA.5, AY4/BA.1 "Deltacron", Alpha (B.1.1.7), BA.2, Beta (B.1.351), Delta (B.1.617.2), Delta Plus (AY.2), Delta Plus (AY4.2), Epsilon (B.1.427/429), Epsilon (B.1.429), Eta (B.1.525), Gamma (P.1), Kappa (B.1.617.1), Lambda (C.37), Mu (B.1.621), Omicron (B.1.1.529), (B.1.1.207), (B.1.1.298), (B.1.2), (B.1.258), (B.1.494)
Tag None, His Tag, GFP Tag
SKU: N/A Category: Tags: , , , , ,

Product Description

SARS-CoV-2 Protein Expression Vectors

The SARS-CoV-2 protein expression vectors are full-length, and codon optimized for mammalian cell expression. Choose to add a GFP or his tag to the C terminal end of any protein. A CMV promoter is used for mammalian cell expression and the backbone contains a selection marker for Geneticin (G418). The amino acid changes to the spike variants are found below. All non-tagged spike protein expression vectors have been functionally validated using pseudotyped viral particles.

Example plasmid map:

Don’t See the specific protein of interest? Email: info@virongy.com to ask us about a custom expression vector order.

SARS-CoV-2 Spike Protein Variants Available: 

SARS-CoV-2 Spikes Available Spike Mutations Full Protein Sequences
D614G Single AA Mutant Spike D614G
Alpha (B.1.1.7)

Spike A570D, Spike D614G, Spike D1118H, Spike H69del, Spike N501Y, Spike P681H, Spike S982A, Spike T716I, Spike V70del, Spike Y145del
(B.1.1.207)

Spike D614G, Spike E484K, Spike P681H
(B.1.1.298)

Spike D614G, Spike H69del, Spike I692V, Spike M1229I, Spike V70del, Spike Y453F
(B.1.2)

Spike D614G, Spike E484K, Spike G446V, Spike Y453F
(B.1.258)
Spike D614G, Spike H69del, Spike N439K, Spike V70del
Beta (B.1.351) Spike A243del, Spike A701V, Spike D80A, Spike D215G, Spike D614G, Spike E484K, Spike K417N, Spike L242del, Spike L244del, Spike N501Y
Epsilon (B.1.429)
Spike A222V, Spike D614G, Spike L452R, Spike S13I, Spike W152C
(B.1.494)
Spike A262S, Spike D614G, Spike D796Y, Spike H49Y, Spike L452R, Spike N501Y, Spike P681R, Spike Q613H
Gamma (P.1)Spike D138Y, Spike D614G, Spike E484K, Spike H655Y, Spike K417T, Spike L18F, Spike N501Y, Spike P26S, Spike R190S, Spike T20N, Spike T1027I, Spike V1176F
Kappa (B.1.617.1) Spike E154K, Spike L452R, Spike E484Q, Spike D614G, Spike P681R, Spike Q1071H
Eta (B.1.525)
Spike A67V, Spike D614G, Spike E484K, Spike F888L, Spike H69del, Spike Q52R, Spike Q677H, Spike V70del, Spike Y144del
Epsilon (B.1.427/429)
Spike D614G, Spike E484K, Spike L452R, Spike S13I, Spike W152C
Delta (B.1.617.2)
Spike T19R, Spike del157/158, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N
Delta Plus (AY.2)
Spike T19R, Spike V70F, Spiked del157/158, Spike A222V, Spike K417N, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N
Lambda (C.37)Spike G75V, Spike T76I, Spike R246N, Spike del247/253, Spike L452Q, Spike F490S, Spike D614G, Spike T859N
Mu (B.1.621)Spike T95I, Spike Y144S, Spike Y145N, Spike R346K, Spike E484K, Spike N501Y, Spike D614G, Spike P681H, Spike D950N
Delta Plus (AY4.2)Spike T19R, Spike T95I, Spike G142D, Spike Y145H, Spike E156G, Spike del157/158, Spike A222V, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N
Omicron (B.1.1.529)Spike A67V, Spike H69del,Spike V70del, Spike T95I, Spike G142D, Spike V143del, Spike Y144del, Spike Y145del, Spike N211del, Spike L212I, Spike ins214EPE, Spike G339D, Spike S371L, Spike S373P, Spike S375F, Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike N969K, Spike L981F
BA.2 Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
AY.4/BA.1Spike T19R, Spike A27S, Spike T95I, Spike G142D, Spike E156G, Spike F157del, Spike R158del, Spike ins214EPE, Spike N211del, Spike L212I, Spike G339D, Spike S371L, Spike S373P, Spike S375F Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike L981F, Spike N969K
BA.4 and BA.5 (Share the Same Spike Mutations) Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D,Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.2.12.1Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452Q, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike S704L, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.2.75Spike T19I, Spike K147E, Spike W152R, Spike F157L, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.4.6Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N658S, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BQ.1Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P,Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BQ.1.1Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P,Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1.5 Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1.16Spike T19I, Spike L24S, Spike 25/27del, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, SpikeE180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S,Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1.9.1Spike T19I, Spike L24S, Spike Del25/27, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.2.86
EG.5.1
FL.1.5.1
HV.1

Technical Specifications

SARS-CoV-2 Spike protein expression vectors are full-length, non-tagged, and codon optimized for mammalian cell expression. The gene is driven by a CMV promoter and the backbone contains a selection marker for Geneticin (G418).

SARS-CoV-2 Spikes Available Spike Mutations Full Protein Sequences
D614G Single AA Mutant Spike D614G
Alpha (B.1.1.7)

Spike A570D, Spike D614G, Spike D1118H, Spike H69del, Spike N501Y, Spike P681H, Spike S982A, Spike T716I, Spike V70del, Spike Y145del
(B.1.1.207)

Spike D614G, Spike E484K, Spike P681H
(B.1.1.298)

Spike D614G, Spike H69del, Spike I692V, Spike M1229I, Spike V70del, Spike Y453F
(B.1.2)

Spike D614G, Spike E484K, Spike G446V, Spike Y453F
(B.1.258)
Spike D614G, Spike H69del, Spike N439K, Spike V70del
Beta (B.1.351) Spike A243del, Spike A701V, Spike D80A, Spike D215G, Spike D614G, Spike E484K, Spike K417N, Spike L242del, Spike L244del, Spike N501Y
Epsilon (B.1.429)
Spike A222V, Spike D614G, Spike L452R, Spike S13I, Spike W152C
(B.1.494)
Spike A262S, Spike D614G, Spike D796Y, Spike H49Y, Spike L452R, Spike N501Y, Spike P681R, Spike Q613H
Gamma (P.1)Spike D138Y, Spike D614G, Spike E484K, Spike H655Y, Spike K417T, Spike L18F, Spike N501Y, Spike P26S, Spike R190S, Spike T20N, Spike T1027I, Spike V1176F
Kappa (B.1.617.1) Spike E154K, Spike L452R, Spike E484Q, Spike D614G, Spike P681R, Spike Q1071H
Eta (B.1.525)
Spike A67V, Spike D614G, Spike E484K, Spike F888L, Spike H69del, Spike Q52R, Spike Q677H, Spike V70del, Spike Y144del
Epsilon (B.1.427/429)
Spike D614G, Spike E484K, Spike L452R, Spike S13I, Spike W152C
Delta (B.1.617.2)
Spike T19R, Spike del157/158, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N
Delta Plus (AY.2)
Spike T19R, Spike V70F, Spiked del157/158, Spike A222V, Spike K417N, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N
Lambda (C.37)Spike G75V, Spike T76I, Spike R246N, Spike del247/253, Spike L452Q, Spike F490S, Spike D614G, Spike T859N
Mu (B.1.621)Spike T95I, Spike Y144S, Spike Y145N, Spike R346K, Spike E484K, Spike N501Y, Spike D614G, Spike P681H, Spike D950N
Delta Plus (AY4.2)Spike T19R, Spike T95I, Spike G142D, Spike Y145H, Spike E156G, Spike del157/158, Spike A222V, Spike L452R, Spike T478K, Spike D614G, Spike P681R, Spike D950N
Omicron (B.1.1.529)Spike A67V, Spike H69del,Spike V70del, Spike T95I, Spike G142D, Spike V143del, Spike Y144del, Spike Y145del, Spike N211del, Spike L212I, Spike ins214EPE, Spike G339D, Spike S371L, Spike S373P, Spike S375F, Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike N969K, Spike L981F
BA.2 Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
AY.4/BA.1Spike T19R, Spike A27S, Spike T95I, Spike G142D, Spike E156G, Spike F157del, Spike R158del, Spike ins214EPE, Spike N211del, Spike L212I, Spike G339D, Spike S371L, Spike S373P, Spike S375F Spike K417N, Spike N440K, Spike G446S, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike G496S, Spike Q498R, Spike N501Y, Spike Y505H, Spike T547K, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike N856K, Spike Q954H, Spike L981F, Spike N969K
BA.4 and BA.5 (Share the Same Spike Mutations) Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D,Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.2.12.1Spike T19I, Spike L24del, Spike P25del, Spike P26del, Spike A27S, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452Q, Spike S477N, Spike T478K, Spike E484A, Spike Q493R, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike S704L, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.2.75Spike T19I, Spike K147E, Spike W152R, Spike F157L, Spike I210V, Spike V213G, Spike G257S, Spike G339H, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.4.6Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike L452R, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N658S, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BQ.1Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike S371F, Spike S373P,Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BQ.1.1Spike T19I, Spike L24S, Spike del25/27, Spike del69/70, Spike G142D, Spike V213G, Spike G339D, Spike R346T, Spike S371F, Spike S373P,Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike K444T, Spike L452R, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486V, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486S, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1.5 Spike T19I, Spike L24S, Spike del25/27, Spike V83A, Spike G142D,Spike del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N,Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1.16Spike T19I, Spike L24S, Spike 25/27del, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, SpikeE180V, Spike Q183E, Spike V213E, Spike G252V, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S,Spike N460K, Spike S477N, Spike T478R, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
XBB.1.9.1Spike T19I, Spike L24S, Spike Del25/27, Spike V83A, Spike G142D, Spike Del144/144, Spike H146Q, Spike Q183E, Spike V213E, Spike G339H, Spike R346T, Spike L368I, Spike S371F, Spike S373P, Spike S375F, Spike T376A, Spike D405N, Spike R408S, Spike K417N, Spike N440K, Spike V445P, Spike G446S, Spike N460K, Spike S477N, Spike T478K, Spike E484A, Spike F486P, Spike F490S, Spike Q498R, Spike N501Y, Spike Y505H, Spike D614G, Spike H655Y, Spike N679K, Spike P681H, Spike N764K, Spike D796Y, Spike Q954H, Spike N969K
BA.2.86
EG.5.1
FL.1.5.1
HV.1

Documentation

Protein Expression Vectors – MSDS

Example plasmid map

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